2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during Inflammation
Anna-Karin Tiden, Tove Sjogren, Mats Svensson, Alexandra Bernlind, Revathy Senthilmohan, Francoise Auchere, Henrietta Norman, Per-Olof Markgren, Susanne Gustavsson, Staffan Schmidt, Stefan Lundquist, Louisa V Forbes, Nicholas J Magon, Louise N Paton, Guy NL Jameson, Hakan Eriksson, Anthony J Kettle
Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2011
A.-K. T., T. S., M. S., A. B., H. N., P.-O. M., S. G., S. S., S. L., and H. E. were employed by AstraZeneca when involved in this study. The following authors own stocks or stock options of AstraZeneca plc.: H. E., A.-K. T., T. S., P.-O. M., H. N., A. B., M. S., S. S., S. G., and S. L. A. J. K. received financial support from AstraZeneca to conduct this research.