Journal article
Revisiting pulmonary vein isolation alone for persistent atrial fibrillation: A systematic review and meta-analysis
A Voskoboinik, JT Moskovitch, N Harel, P Sanders, PM Kistler, JM Kalman
Heart Rhythm | Published : 2017
Abstract
Background Early studies demonstrated relatively low success rates for pulmonary vein isolation (PVI) alone in patients with persistent atrial fibrillation (PeAF). However, the advent of new technologies and the observation that additional substrate ablation does not improve outcomes have created a new focus on PVI alone for treatment of PeAF. Objective The purpose of this study was to systematically review the recent medical literature to determine current medium-term outcomes when a PVI-only approach is used for PeAF. Methods An electronic database search (MEDLINE, Embase, Web of Science, PubMed, Cochrane) was performed in August 2016. Only studies of PeAF patients undergoing a ”PVI only” ..
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Funding Acknowledgements
Dr. Voskoboinik is supported by a co-funded National Health and Medical Research Council of Australia (NHMRC)/National Heart Foundation of Australia (NHF) postgraduate scholarship and Baker IDI Bright Sparks scholarship. Profs. Kistler, Sanders, and Kalman are supported by practitioner fellowships from the NHMRC. Prof. Sanders is also supported by a practitioner fellowship from the NHF. This research is supported in part by the Victorian Government's Operational Infrastructure Funding. Prof. Kalman sits on the advisory board of Biosense Webster and Boston Scientific; and receives research and fellowship support from Biosense Webster, Boston Scientific, St. Jude Medical, and Medtronic. Prof. Sanders has served on the advisory board of Biosense Webster, Medtronic, and St. Jude Medical; has received lecture fees from Biosense Webster, Medtronic, St. Jude Medical, Boston Scientific, and Merck; and has received research funding from Medtronic, St. Jude Medical, Boston Scientific, Biotronik, and Sorin. Address reprint requests and correspondence: Prof. Jonathan M. Kalman, Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia. E-mail address: jon.kalman@mh.org.au.