Comparative effectiveness of routine invasive coronary angiography for managing unstable angina

Abstract

Background: Non-ST-segment elevation acute coronary syndromes include unstable angina and non-ST-segment elevation myocardial infarction. Most randomized controlled trials of routine versus selective invasive coronary angiography have high rates of crossover from control to intervention groups and do not include subgroup analysis for unstable angina. Consequently, no clear, specific recommendations exist regarding the use of angiography in unstable angina. Objective: To assess the effect of angiography on mortality in unstable angina, incorporating the results of additional cardiac procedures and events. Design: Longitudinal study using hospital discharge data, discrete-time survival analysi..