Journal article

Oxidative stress markers, cognitive functions, and psychosocial functioning in bipolar disorder: An empirical cross-sectional study

Ö Aydemir, Z Çubukçuoğlu, S Erdin, C Taş, E Onur, M Berk

Revista Brasileira De Psiquiatria | ASSOC BRASILEIRA PSIQUIATRIA | Published : 2014

Open access

Abstract

Objective: This study aimed to evaluate the relationship between oxidative stress markers and cognitive functions and domains of psychosocial functioning in bipolar disorder.Methods: Oxidative stress markers, cognitive functions, and domains of psychosocial functioning were evaluated in 51 patients with bipolar disorder who were in remission. Correlation analyses between these parameters were calculated with data controlled for duration of illness and number of episodes.Results: There was no statistically significant correlation between oxidative stress markers and cognitive functions. In terms of psychosocial functioning, significant correlations were found between malondialdehyde and sense..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

OA has participated in a multicenter study sponsored by AstraZeneca; has served as a speaker for Lundbeck, AstraZeneca, Janssen-Cilag, and Pfizer; and has served as a consultant for Servier. MB has received grant/ research support from the National Institutes of Health (NIH), Cooperative Research Centre, Simons Autism Foundation, Cancer Council of Victoria, Stanley Medical Research Foundation, MBF, NHMRC, Beyond Blue, Rotary Health, the Geelong Medical Research Foundation, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Meat and Livestock Board, Organon, Novartis, MaynePharma, Servier, and Woolworths; has served as a speaker for AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen-Cilag, Lundbeck, Merck, Pfizer, SanofiSynthelabo, Servier, Solvay, and Wyeth; and has served as a consultant for AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen-Cilag, Lundbeck Merck, and Servier. The other authors report no conflicts of interest.