Journal article

The DNA sequence of human chromosome 22.

I Dunham, N Shimizu, BA Roe, S Chissoe, AR Hunt, JE Collins, R Bruskiewich, DM Beare, M Clamp, LJ Smink, R Ainscough, JP Almeida, A Babbage, C Bagguley, J Bailey, K Barlow, KN Bates, O Beasley, CP Bird, S Blakey Show all

Nature | Published : 1999

Abstract

Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those without known function, their control elements, and, by inference, the proteins they encode, as well as all other biologically important sequences. Furthermore, the sequence is a rich and permanent source of information for the design of further biological studies of the organism and for the study of evolution through cross-species sequence comparison. The power of this approach has been amply demonstrated by the determination of the sequences of a number of microbial and mo..

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