Quantifying errors in the estimation of tuberculosis mortality in a population of South African miners.
P Sonnenberg, MSC Lim, RJ Dowdeswell, N Field, JR Glynn, J Murray
Int J Tuberc Lung Dis | Published : 2012
BACKGROUND: All-cause mortality, based on national tuberculosis programme (NTP) register deaths, may under- or overestimate tuberculosis (TB) specific mortality in the population. OBJECTIVE: To assess the factors influencing this measurement in a single large population with high TB prevalence and mortality. METHODS: Routinely collected data on TB cases and treatment outcomes were linked to population data from a cohort of South African miners from 1995 to 2008. Vital status and cause of death were determined from multiple sources, including the TB programme, death register and autopsy. RESULTS: The TB mortality rate, based on 430 deaths on the TB register, was 192/100,000 person-years (py)...View full abstract
Awarded by National Institute for Health Research (NIHR)