Journal article

Seroprevalence of Seasonal and Pandemic Influenza A in Kuala Lumpur, Malaysia in 2008-2010

I-Ching Sam, Robert Shaw, Yoke-Fun Chan, Poh-Sim Hooi, Aeron C Hurt, Ian G Barr

JOURNAL OF MEDICAL VIROLOGY | WILEY | Published : 2013

Abstract

Relatively little is known about the burden of influenza in tropical countries. The seroprevalence of pandemic influenza A (H1N1) 2009, seasonal H1N1 and H3N2 was determined in Kuala Lumpur, Malaysia. Pre- and post-pandemic residual laboratory sera were tested by hemagglutination-inhibition. The seroprevalence of A(H1N1)pdm09 increased from 3.7% pre-pandemic to 21.9% post-pandemic, giving an overall cumulative incidence of 18.1% (95% CI, 13.8-22.5%), mainly due to increases in those 55 years. A(H1N1)pdm09 affected almost a third of those <30 years in Kuala Lumpur. Pre-pandemic seroprevalence was 14.7% for seasonal H1N1 and 21.0% for H3N2, and these rates did not change significantly after th..

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Grants

Awarded by University Malaya


Funding Acknowledgements

Grant sponsor: Melbourne WHO Collaborating Centre for Reference and Research on Influenza (Australian Government Department of Health and Ageing); Grant sponsor: University Malaya (High Impact Research Grant).; Grant number: UM.C/625/1/HIR/MOHE/MED/42