Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

Abstract

An influenza B virus from an infant with no history of treatment or contact with neuraminidase inhibitors demonstrated a significant reduction in sensitivity to these drugs. Here, we describe the analysis of a mixed viral population that contained a novel D197E amino acid substitution that was responsible for this reduction. Copyright © 2006, American Society for Microbiology. All Rights Reserved.