Postprandial plasma phospholipids in men are influenced by the source of dietary fat

Abstract

Background: Postprandial lipemia represents a risk factor for chronic diseases, including type 2 diabetes. Little is known about the effect of dietary fat on the plasma lipidome in the postprandial period. Objective: The objective of this study was to assess the effect of dairy fat and soy oil on circulating postprandial lipids in men. Methods: Men (40-60 y old, nonsmokers; n = 16) were randomly assigned in a crossover design to consume 2 breakfast meals of dairy-based or soy oil-based foods. The changes in the plasma lipidome during the 4-h postprandial period were analyzed with electrospray ionization tandem mass spectrometry and included 316 lipid species in 23 classes and subclasses, rep..