Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance
Darren C Henstridge, E Estevez, TL Allen, SE Heywood, T Gardner, C Yang, NA Mellett, BA Kingwell, PJ Meikle, MA Febbraio
Cell Stress and Chaperones | SPRINGER | Published : 2015
Awarded by National Health and Medical Research Council of Australia (NHMRC)
We wish to acknowledge Deb Ramsey and her team at the AMREP AS for their assistance with the animal studies, Jacqui Weir for technical assistance, and Helene Kammoun for critically reviewing the manuscript. This study was supported by grants from the National Health and Medical Research Council of Australia (NHMRC Project Grant 1004441) and the Victorian Government Operational Infrastructure Support Program. MAF and BAK (1059454) are Senior Principal Research Fellows of the NHMRC. PJM is a Senior Research Fellow of the NHMRC. DCH is supported by a National Heart Foundation (NHF) Biomedical Postdoctoral Fellowship and an Australian Diabetes Society (ADS) Skip Martin Fellowship. The original Hsp72 Tg mouse line was provided by Prof Ruben Mestril.