Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia
Alexina Orsoni, Patrice Therond, Ricardo Tan, Philippe Giral, Paul Robillard, Anatol Kontush, Peter J Meikle, M John Chapman
The Journal of Lipid Research | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2016
The authors are indebted to Kowa Research Europe for the award of a Clinical Research Grant to support all aspects of the CAPITAIN study and lipidomic analyses (ClinicalTrials.gov, #NCT01595828), and to Institut National de la Sante et de la Recherche Medicale, the Nouvelle Societe Franaise d'Atherosclerose, and the Association for Research on Lipoproteins and Atherogenesis (ARLA) for additional support. A. Orsoni gratefully acknowledges the award of a postdoctoral fellowship from ARLA. This work was equally supported by funding from the National Health and Medical Research Council of Australia (NHMRC), the Operational Infrastructure Support (OIS) Program of the State Government of Victoria, Australia. P. J. Meikle is supported by an NHMRC Senior Research Fellowship. The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the aforementioned funding bodies.