Measures of disease status in systemic sclerosis: A systematic review

Abstract

Objectives To identify and appraise measures of disease status in systemic sclerosis (SSc). Methods A systematic review of Medline (1966–2015), EMBASE (1974–2015), and Cochrane Library (inception–2015) was undertaken to identify indices of disease status in SSc. We focused on objective measures and excluded non-English articles. Measures were reviewed for content, whether they measured activity, damage and/or severity and whether they were validated according to the OMERACT filter. Results Of the 4558 articles retrieved through the search, we identified 58 articles for review. We found a further 44 articles through a search of the bibliography of relevant articles. We identified the followin..