[The role and importance of cognitive symptoms in bipolar disorder].

Abstract

OBJECTIVE: Our aim was to review evidence of the role of cognitive deficits in bipolar disorder and their relationship to other factors, such as disorder variables, treatment, additional diagnoses, genetic risk, and brain imaging findings. METHOD: Studies that examined cognitive dysfunction in bipolar disorder and its relationship to the variables of clinical, genetic, and bipolar disorder subtypes, as well as neuro-anatomical and neuro-functional evidence have been reviewed. Findings from our own studies have also been used while conducting the review. RESULTS: In bipolar disorder, deficits in executive functions, memory, and attention persist in the euthymic state. The number of episodes a..