Journal article

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

Isabel Jaco, Alessandro Annibaldi, Najoua Lalaoui, Rebecca Wilson, Tencho Tenev, Lucie Laurien, Chun Kim, Kunzah Jamal, Sidonie Wicky John, Gianmaria Liccardi, Diep Chau, James M Murphy, Gabriela Brumatti, Rebecca Feltham, Manolis Pasparakis, John Silke, Pascal Meier

Molecular Cell | CELL PRESS | Published : 2017

Grants

Awarded by Breast Cancer Now


Awarded by World Wide Cancer Research grant


Awarded by MRC


Awarded by ERC


Awarded by NHMRC


Awarded by Australian Government NHMRC IRIISS


Awarded by Victoria Cancer Agency mid-career fellowship


Funding Acknowledgements

We would like to thank M. Gaestel for tissue from Mk2<SUP>-/-</SUP> mice. We thank members of the Meier, Silke, and Pasparakis laboratories for helpful discussions and the CECAD Transgenic Core Facility for CRISPR/Cas9 mutagenesis in mouse zygotes. R.W., G.L., and T.T. are supported by Breast Cancer Now CTR-QR14-007. I.J. is supported by a World Wide Cancer Research grant (14-1328) and Breast Cancer Now CTR-QR14-007. A. A. is supported by the MRC grant MR/M019217/7. P.M. acknowledges NHS funding to the NIHR Biomedical Research Centre. M.P. acknowledges funding from the ERC (grant agreement no. 323040). N.L is supported by World Wide Cancer Research grant 15-0042. This work was funded by NHMRC grants 1025594, 1046984, 1081221, and 1081376 and was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS (9000220). J.S. is supported by fellowship 1107149 from the NHMRC. G.B. is supported by a Victoria Cancer Agency mid-career fellowship (VCA-MCRF15027). J.M.M. is supported by fellowship 1105754 from NHMRC. R.F. acknowledges funding from NHMRC 1081272.