Journal article
Population-based study of grade progression in patients who harboured Gleason 3 3
F Sampurno, A Earnest, J Millar, M Frydenberg, D Murphy, W Delprado, S Evans
World Journal of Urology | SPRINGER | Published : 2017
Abstract
Purpose: This study aimed to evaluate (1) the time interval between a decision to commence on active surveillance (AS) and grade progression in community practice; (2) factors predicting grade progression in localised prostate cancer (CaP) patients apparently undergoing AS. Methods: Data from the Prostate Cancer Outcomes Registry—Victoria were used to analyze men with Gleason 3 + 3 CaP or less who had at least one repeat biopsy. Unadjusted and adjusted 5-year Kaplan–Meier survival curves were used to assess the time to grade progression. Both univariate and multivariate analyses for grade progression were performed using Cox proportional hazards. Results: The cohort included 951 men. Overall..
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Funding Acknowledgements
We would like to thank the participating clinicians and data collectors for their valuable contribution to the PCOR-Vic. We would also like to gratefully acknowledge Movember Foundation for funding support for this project.