Journal article

Analytical evidence of enamel hypomineralisation on permanent and primary molars amongst past populations

Elsa Garot, Christine Couture-Veschambre, David Manton, Cedric Beauval, Patrick Rouas



Molar Incisor Hypomineralisation (MIH) and Hypomineralised Second Primary Molars (HSPM) involve prevalent qualitative structural developmental anomalies of tooth enamel affecting the first permanent molars (and often incisors) and the second primary molars, respectively. These demarcated hypomineralised lesions of enamel manifest as white-cream or yellow-brown opacities, with possible post-eruptive localised loss of enamel. Aetiological hypotheses have involved contemporary life factors (i.e. environmental pollutant exposure or early childhood medications) in contrast to factors not limited to a specific time period (i.e. hypoxia at birth or genetic predisposition). Evidence of MIH in ancien..

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University of Melbourne Researchers


Awarded by PRC CNRS-University of Melbourne

Awarded by ANR

Funding Acknowledgements

This work was supported by the Institut Francais de Recherche Odontologique (IFRO) and the PRC CNRS-University of Melbourne (No 501911 GL). Thanks are due to Patrice Courtaud (CNRS, UMR 5199, PACEA, Bordeaux University) and Jean-Marc Femolant (director of the Archeological Service of Beauvais) for access to the osteological series of the "Couvent des Soeurs Grises". We gratefully acknowledge Frederic Santos (CNRS, UMR 5199, PACEA, Bordeaux University) for his help with statistics. Nicolas Lenoir (PLACAMAT, UMS 3626-CNRS/Bordeaux University), Ronan Ledevin (LabEx LaScArBx, UMR 5199 PACEA/Bordeaux University), Yannick Lefrais (IRAMAT-CRP2A, UMR 5060) and the 19 anonymous MIH specialists are acknowledged for their contributions to the study. LaScArBx is a research programme supported by the ANR (ANR-10-LABX-52).