Sensory integration deficits support a dimensional view of psychosis and are not limited to schizophrenia
O Carter, D Bennett, T Nash, S Arnold, L Brown, RY Cai, Z Allan, A Dluzniak, K McAnally, D Burr, S Sundram
TRANSLATIONAL PSYCHIATRY | NATURE PUBLISHING GROUP | Published : 2017
Visual dysfunction is commonplace in schizophrenia and occurs alongside cognitive, psychotic and affective symptoms of the disorder. Psychophysical evidence suggests that this dysfunction results from impairments in the integration of low-level neural signals into complex cortical representations, which may also be associated with symptom formation. Despite the symptoms of schizophrenia occurring in a range of disorders, the integration deficit has not been tested in broader patient populations. Moreover, it remains unclear whether such deficits generalize across other sensory modalities. The present study assessed patients with a range of psychotic and nonpsychotic disorders and healthy con..View full abstract
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OC has received research and salary support from the Australian National Health and Medical Research Council and the Australian Research Council. SS has received consulting fees, advisory board fees, research support, speakers honoraria or travel support from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Flack trust, GlaxoSmithKline, the Australian National Health and Medical Research Council, One-in-Five Association, Pfizer and Roche. The remaining authors declare no conflict of interest.