Temporal Global Expression Data Reveal Known and Novel Salicylate-Impacted Processes and Regulators Mediating Powdery Mildew Growth and Reproduction on Arabidopsis
Divya Chandran, Yu Chuan Tai, Gregory Hather, Julia Dewdney, Carine Denoux, Diane G Burgess, Frederick M Ausubel, Terence P Speed, Mary C Wildermuth
PLANT PHYSIOLOGY | AMER SOC PLANT BIOLOGISTS | Published : 2009
Salicylic acid (SA) is a critical mediator of plant innate immunity. It plays an important role in limiting the growth and reproduction of the virulent powdery mildew (PM) Golovinomyces orontii on Arabidopsis (Arabidopsis thaliana). To investigate this later phase of the PM interaction and the role played by SA, we performed replicated global expression profiling for wild-type and SA biosynthetic mutant isochorismate synthase1 (ics1) Arabidopsis from 0 to 7 d after infection. We found that ICS1-impacted genes constitute 3.8% of profiled genes, with known molecular markers of Arabidopsis defense ranked very highly by the multivariate empirical Bayes statistic (T(2) statistic). Functional anal..View full abstract
Awarded by National Science Foundation
Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
This work was supported by the National Science Foundation (Arabidopsis 2010 grant nos. MCB-0420267 to M. C. W. and T. P. S. and DBI-0114783 to X. Dong, S. Somerville, and F. M. A.) and the Winkler Family Foundation (grant to M. C. W.).