Journal article
Inhibitory effect of syphilitic rabbit serum on DNA synthesis in rabbit cells in vitro
GHW Wong, B Steiner, R Strugnell, S Faine, S Graves
Sexually Transmitted Infections | BMJ PUBLISHING GROUP | Published : 1984
DOI: 10.1136/sti.60.5.285
Abstract
A previously described toxic factor associated with Treponema pallidum (Nichols) and found in extracts of syphilitic rabbit testes has now also been detected in syphilitic rabbit serum. The toxic factor, which inhibits DNA synthesis in baby rabbit genital organ (BRGO) cells in vitro, is present in rabbit serum up to 30 days after infection with Tpallidum.