Journal article

GLUCOSE KINETICS DURING EXERCISE IN TRAINED MEN

M HARGREAVES, J PROIETTO

ACTA PHYSIOLOGICA SCANDINAVICA | BLACKWELL SCIENCE LTD | Published : 1994

Abstract

Six trained men were studied to examine the relative increases in hepatic glucose output and peripheral glucose uptake during 40 min of exercise at 75% VO2max. Rates of appearance (Ra) and disappearance (Rd) were measured using a primed, continuous intravenous infusion of D-[3-3H]glucose. Plasma glucose increased (P < 0.05) from 4.8 +/- 0.2 mmol l-1 at rest to 6.2 +/- 0.5 mmol l-1 after 40 min of exercise. Both Ra and Rd increased (P < 0.05) during exercise, however, during the early phase of exercise, Ra exceeded Rd (P < 0.05). Ra peaked at 42.0 +/- 3.2 mumol kg-1 min-1 after approximately 15 min of exercise. In contrast, the highest Rd of 33.9 +/- 4.3 mumol kg-1 min-1 was measured at the e..

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University of Melbourne Researchers