Journal article

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

Gregory A Roth, Catherine Johnson, Amanuel Abajobir, Foad Abd-Allah, Semaw Ferede Abera, Gebre Abyu, Muktar Ahmed, Baran Aksut, Tahiya Alam, Khurshid Alam, Francois Alla, Nelson Alvis-Guzman, Stephen Amrock, Hossein Ansari, Johan Arnlov, Hamid Asayesh, Tesfay Mehari Atey, Leticia Avila-Burgos, Ashish Awasthi, Amitava Banerjee Show all



BACKGROUND: The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. OBJECTIVES: The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden. METHODS: CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specif..

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Awarded by National Institute for Health Research

Funding Acknowledgements

The Institute for Health Metrics and Evaluation received funding from the Bill & Melinda Gates Foundation. The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Dr. Arnlov has received lecturing fees from AstraZeneca. Dr. Fowkes has served on the advisory boards of AstraZeneca, Merck, and Bayer. Dr. Hankey has received honoraria from Bayer for lecturing at sponsored scientific symposia about stroke prevention in atrial fibrillation. Dr. Khubchandani has received research funding from Merck Laboratories. Dr. Lotufo has received honoraria from Amgen Brazil and AbbVie Brazil. Dr. Rahimi's research is supported by grants from the National Institute for Health Research Oxford Biomedical Research Centre, National Institute for Health Research Career Development Fellowship, and Oxford Martin School. Dr. Schutte is a speaker to general practitioners and cardiologists on hypertension guidelines (funded by Boehringer Ingelheim), to cardiologists on health behaviors and cardiovascular diseases (funded by Novartis), and to nurses and pharmacists on arterial stiffness and blood pressure (funded by Omron Healthcare and I.E.M.). Dr. Watkins is funded by Medtronic Foundation through support to RhEACH and RHD Action, and by the Disease Control Priorities Network grant from the Bill and Melinda Gates Foundation. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.