Characterisation of the canine faecal virome in healthy dogs and dogs with acute diarrhoea using shotgun metagenomics
Paloma S Moreno, Josef Wagner, Caroline S Mansfield, Matthew Stevens, James R Gilkerson, Carl D Kirkwood
PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2017
The virome has been increasingly investigated in numerous animal species and in different sites of the body, facilitating the identification and discovery of a variety of viruses. In spite of this, the faecal virome of healthy dogs has not been investigated. In this study we describe the faecal virome of healthy dogs and dogs with acute diarrhoea in Australia, using a shotgun metagenomic approach. Viral sequences from a range of different virus families, including both RNA and DNA families, and known pathogens implicated in enteric disease were documented. Twelve viral families were identified, of which four were bacteriophages. Eight eukaryotic viral families were detected: Astroviridae, Co..View full abstract
PSM is supported by Becas Chile scholarship program, Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT), Chilean government (http://www.conicyt.cl/becas-conicyt). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.