Effects of glycaemic management on diabetic kidney disease
Richard J MacIsaac, George Jerums, Elif I Ekinci
WORLD JOURNAL OF DIABETES | BAISHIDENG PUBLISHING GROUP INC | Published : 2017
Hyperglycaemia contributes to the onset and progression of diabetic kidney disease (DKD). Observational studies have not consistently demonstrated a glucose threshold, in terms of HbA1c levels, for the onset of DKD. Tight glucose control has clearly been shown to reduce the incidence of micro- or macroalbuminuria. However, evidence is now also emerging to suggest that intensive glucose control can slow glomerular filtration rate loss and possibly progression to end stage kidney disease. Achieving tight glucose control needs to be balanced against the increasing appreciation that glucose targets for the prevention of diabetes related complications need be individualised for each patient. Rece..View full abstract
Supported by ADS-Sevier Research Grant (to MacIsaac RJ).