Allergic adverse events following 2015 seasonal influenza vaccine, Victoria, Australia
HJ Clothier, N Crawford, MA Russell, JP Buttery
EUROSURVEILLANCE | EUR CENTRE DIS PREVENTION & CONTROL | Published : 2017
Australia was alerted to a possible increase in allergy-related adverse events following immunisation (AEFI) with 2015 seasonal trivalent influenza vaccines (TIV) by the Victorian state vaccine safety service, SAEFVIC. We describe SAEFVIC's initial investigation and upon conclusion of the 2015 influenza vaccination programme, to define the signal event and implications for vaccine programmes. Allergy-related AEFI were defined as anaphylaxis, angioedema, urticaria or generalised allergic reaction. Investigations compared 2015 TIV AEFI reports to previous years as proportions and reporting risk (RR) per 100,000, stratified by influenza vaccine brand. The initial investigation showed an increas..View full abstract
SAEFVIC is funded under a contract with the Victorian Government Department of Health. Hazel J Clothier is a recipient of an Australian Postgraduate Award. The authors wish to thank Heath Kelly for reviewing the manuscript and also to acknowledge the contribution of the SAEFVIC immunisation nurses for their implementation of the SAEFVIC surveillance system.