Journal article
Burden and impact of Plasmodium vivax in pregnancy: A multi-centre prospective observational study
A Bardají, FE Martínez-Espinosa, M Arévalo-Herrera, N Padilla, S Kochar, M Ome-Kaius, C Bôtto-Menezes, ME Castellanos, DK Kochar, SK Kochar, I Betuela, I Mueller, S Rogerson, C Chitnis, D Hans, M Menegon, C Severini, H del Portillo, C Dobaño, A Mayor Show all
Plos Neglected Tropical Diseases | Published : 2017
Abstract
Background: Despite that over 90 million pregnancies are at risk of Plasmodium vivax infection annually, little is known about the epidemiology and impact of the infection in pregnancy. Methodology and principal findings: We undertook a health facility-based prospective observational study in pregnant women from Guatemala (GT), Colombia (CO), Brazil (BR), India (IN) and Papua New Guinea PNG). Malaria and anemia were determined during pregnancy and fetal outcomes assessed at delivery. A total of 9388 women were enrolled at antennal care (ANC), of whom 53% (4957) were followed until delivery. Prevalence of P. vivax monoinfection in maternal blood at delivery was 0.4% (20/4461) by microscopy [G..
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Grants
Awarded by European Commission
Funding Acknowledgements
The PregVax collaborative project was funded by the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement number PREGVAX FP7-HEALTH-201588. It also received co-funding from the Malaria in Pregnancy Consortium (MiPc) through a grant from the Bill & Melinda Gates Foundation [Grant No. 46099], and from the Ministry of Science and Innovation of Spain. Ivo Mueller was supported by a National Health and Medical Research Council (NHMRC) Senior Research Fellowship, Myriam Arevalo-Herrera was supported by the Centro Latino Americano de Investigacion en Malaria (CLAIM) sponsored by NIAID/ICEMR (U19AI089702), and Azucena Bardaji was supported by the Government of Spain, Ramon y Cajal Fellowship [Grant No. RYC-2013-14512]. The study was coordinated by Fundacio Clinic per a la Recerca Biomedica (FCRB) ISGlobal/Barcelona Centre for International Health Research (CRESIB) in Spain, which provided project and data management and logistic support, and co-coordinated by the Centers for Disease Control and Prevention (CDC) in Atlanta, USA. ISGlobal is a member of the CERCA Programme, Generalitat de Catalunya. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.