Substituted arylsulphonamides as inhibitors of perforin-mediated lysis
Julie A Spicer, Christian K Miller, Patrick D O'Connor, Jiney Jose, Kristiina M Huttunen, Jagdish K Jaiswal, William A Denny, Hedieh Akhlaghi, Kylie A Browne, Joseph A Trapani
European Journal of Medicinal Chemistry | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | Published : 2017
Awarded by Wellcome Trust
Awarded by Maurice & Phyllis Paykel Trust (MPPT)
Awarded by Genesis Oncology Trust
This work was supported by the Wellcome Trust (Grant 097767), the Auckland Division of the Cancer Society of New Zealand, the Maurice & Phyllis Paykel Trust (MPPT; Grant Number: 8.2.29) and the Genesis Oncology Trust (Grant Number: GOT-1616-PDA). The authors thank Sisira Kumara for HPLC and solubility work, Karin Tan for HPLC, Maruta Boyd and Shannon Black for NMR studies.