Journal article

Association between prenatal alcohol exposure and craniofacial shape of children at 12 months of age

E Muggli, H Matthews, A Penington, P Claes, C O'Leary, D Forster, S Donath, PJ Anderson, S Lewis, C Nagle, JM Craig, SM White, EJ Elliott, J Halliday

JAMA Pediatrics | AMER MEDICAL ASSOC | Published : 2017

Abstract

IMPORTANCE Children who receive a diagnosis of fetal alcohol spectrum disorder may have a characteristic facial appearance in addition to neurodevelopmental impairment. It is not well understood whether there is a gradient of facial characteristics of children who did not receive a diagnosis of fetal alcohol spectrum disorder but who were exposed to a range of common drinking patterns during pregnancy. OBJECTIVE To examine the association between dose, frequency, and timing of prenatal alcohol exposure and craniofacial phenotype in 12-month-old children. DESIGN, SETTING, AND PARTICIPANTS A prospective cohort studywas performed from January 1, 2011, to December 30, 2014, among mothers recruit..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

This work is supported by grant 1011070 from the Australian National Health and Medical Research Council, Senior Research Fellowships 1081288 (Dr Anderson) and 1021252 (Dr Halliday) from the Australian National Health and Medical Research Council, Practitioner Fellowship 1021480 (Dr Elliott) from the Australian National Health and Medical Research Council, and the Victorian State Government's Operational Infrastructure Support Program.