Engineering tough, highly compressible, biodegradable hydrogels by tuning the network architecture
Dunyin Gu, Shereen Tan, Chenglong Xu, Andrea J O'Connor, Greg G Qiao
CHEMICAL COMMUNICATIONS | ROYAL SOC CHEMISTRY | Published : 2017
By precisely tuning the network architecture, tough, highly compressible hydrogels were engineered. The hydrogels were made by interconnecting high-functionality hydrophobic domains through linear tri-block chains, consisting of soft hydrophilic middle blocks, flanked with flexible hydrophobic blocks. In showing their applicability, the efficient encapsulation and prolonged release of hydrophobic drugs were achieved.