Journal article

Longer-term increased cortisol levels in young people with mental health problems

Kareen Heinze, Ashleigh Lin, Renate LEP Reniers, Stephen J Wood

Psychiatry Research | ELSEVIER IRELAND LTD | Published : 2016


Disturbance of hypothalamus-pituitary-adrenal axis activity is commonly reported in a range of mental disorders in blood, saliva and urine samples. This study aimed to look at longer-term cortisol levels and their association with clinical symptoms. Hair strands of 30 young people (16-25 years) presenting with mental health problems (Mage±SD=21±2.4, 26 females) and 28 healthy controls (HC, Mage±SD=20±2.9, 26 females) were analyzed for cortisol concentrations, representing the past 6 months prior to hair sampling. Clinical participants completed an assessment on psychiatric symptoms, functioning and lifestyle factors. All participants completed the Perceived Stress Scale. Hair cortisol concen..

View full abstract

University of Melbourne Researchers


Awarded by NHMRC

Awarded by MRC Research Grant

Awarded by Medical Research Council

Funding Acknowledgements

This study was partially financially supported by the Pump Priming Research Grant of the Wellcome Trust Institutional Strategic Support Fund. Ashleigh Lin is supported by the NHMRC (#1072593). Renate Reniers is funded by an MRC Research Grant (#MR/K013599/1).