Journal article

Bone turnover marker determinants in young women: results from the Safe-D study

Emma T Callegari, Suzanne M Garland, Alexandra Gorelik, Cherie Y Chiang, John D Wark

ANNALS OF CLINICAL BIOCHEMISTRY | SAGE PUBLICATIONS INC | Published : 2018

Abstract

Background Bone turnover markers (BTMs) may provide insight into bone health in young women, but have been little studied in this demographic. We aimed to explore the association between body composition, hormonal contraception, bone mineral density and biochemical parameters and BTMs in young women. Methods Participants were community-dwelling females aged 16-25 years, living in Victoria, Australia. Carboxy-terminal cross-linking telopeptide of type 1 collagen (CTX) and total procollagen type 1 N-propeptide (P1NP) were analysed on the Roche Elecsys automated analyzer. A total of 305 were evaluated, after excluding participants with medical conditions or medications (except hormonal contrace..

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