Journal article
No effect of a whey growth factor extract during resistance training on strength, body composition, or hypertrophic gene expression in resistance-trained young men
MJ Dale, AM Coates, PRC Howe, GR Tomkinson, MT Haren, A Brown, M Caldow, D Cameron-Smith, JD Buckley
Journal of Sports Science and Medicine | JOURNAL SPORTS SCIENCE & MEDICINE | Published : 2017
Abstract
Growth factors can be isolated from bovine milk to form a whey growth factor extract (WGFE). This study examined whether WGFE promoted activation of the AKT/mTOR pathway enabling increased lean tissue mass and strength in resistance trained men. Forty six men with >6 months of resistance training (RT) experience performed 12 weeks of RT. Participants consumed 20 g/day of whey protein and were randomised to receive either 1.6 g WGFE/day (WGFE; n = 22) or 1.6 g cellulose/day (control, CONT; n = 24). The primary outcome was leg press one-repetition maximum (LP1-RM) which was assessed at baseline, 6 and 12 weeks. At baseline and 12 weeks body composition was assessed by dual energy x-ray absorpt..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
We thank Professor Garry Scroop (MBBS, MD, PhD) for collecting the muscle biopsy samples for this study. All authors contributed to study design. MJD collected the data. MJD, JDB, MKC and DC-S analysed the data. All authors contributed to data interpretation and manuscript preparation. The study was funded by Murray Goulburn Co-Operative Co Ltd. A Brown is an employee of Murray Goulburn Co-operative Co Ltd. The other authors have no conflicts of interest. MT Haren was supported by a Post-doctoral Training Fellowship (Public Health) from the National Health and Medical Research Council (NHMRC) of Australia (# 511345). The experiments described comply with the current laws of Australia, where the research was performed.