Journal article

Determinants of bone mineral density in young Australian women; results from the Safe-D study

ET Callegari, SM Garland, A Gorelik, JD Wark



The study aimed to explore determinants of bone parameters in young women. Most bone parameters were associated with height and lean mass. Bone parameters were not associated with vitamin D status. Future research should address whether interventions aimed at improving lean mass are beneficial to bone health in young women. INTRODUCTION: The implementation of prevention strategies during young adulthood may be crucial for osteoporosis prevention in later life, yet literature examining the determinants of bone health in premenopausal women is limited. We aimed to assess determinants of bone health, including serum 25-hydroxyvitamin D (25OHD), in females aged 16-25 years, living in Victoria, A..

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Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

The authors thank the participants who took part in the Safe-D study. The authors also thank the Safe-D chief investigators Dr. Nicola Reavley, A/Professor Marie Pirotta, Prof George Varigos, A/Prof Shanton Chang, and as well as associate investigators Prof Kim Bennell, Prof Anthony Jorm, and past study coordinator Ms. Adele Rivers. The authors also thank the Young Female Health Initiative (YFHI) associate investigators Dr. Yasmin Jayasinghe, Dr. Catherine Segan, and Dr. Asvini Subasinghe. The authors thank Anna Scobie, Marjan Tabesh, Miaowen Zhou, Lauren Gilbert, and Skye Maclean for assisting with the Safe-D study. We acknowledge the following people for their help with various components of the study: Adrian Bickerstaffe (The University of Melbourne); Maria Bisignano (Melbourne Health Shared Pathology Service); Dr. Ashwini Kale (The University of Melbourne); Dr. Johannes Willnecker (Novotec Medical GmbH). The Safe-D study was funded by National Health and Medical Research Council (NHMRC) project grant APP1049065.