Long-term follow-up of intra-cytoplasmic sperm injection-conceived offspring compared with in vitro fertilization-conceived offspring: a systematic review of health outcomes beyond the neonatal period
SR Catford, RI McLachlan, MK O'Bryan, JL Halliday
ANDROLOGY | WILEY | Published : 2017
The use of intra-cytoplasmic sperm injection (ICSI) has increased significantly worldwide, often chosen instead of in vitro fertilization (IVF), yet long-term health outcomes are unknown and health differences between ICSI and IVF conceptions have not been comprehensively assessed. A systematic review of health outcomes of ICSI-conceived offspring beyond the neonatal period compared to IVF-conceived offspring was carried out. PubMed, OVID Medline/Embase, Informit, Web of Science and Proquest databases were searched on 9 November 2016 for studies reporting on health outcomes in ICSI-conceived offspring beyond 28 days after birth. Physical and psychosocial health were the main outcome measures..View full abstract
Awarded by National Health and Medical Research Council
S.C. is supported through an Australian Government Research Training Program Scholarship. R.M., M.O. and J.H. are supported by the National Health and Medical Research Council as Principal Research Fellows (R.M. fellowship number: 1022327, M.O. fellowship number: 1058356, J.H. fellowship number: 1021252).