Journal article

Quantifiable predictive features define epitope-specific T cell receptor repertoires

Pradyot Dash, Andrew J Fiore-Gartland, Tomer Hertz, George C Wang, Shalini Sharma, Aisha Souquette, Jeremy Chase Crawford, E Bridie Clemens, Thi HO Nguyen, Katherine Kedzierska, Nicole L La Gruta, Philip Bradley, Paul G Thomas

Nature | NATURE PUBLISHING GROUP | Published : 2017


Awarded by NIH

Awarded by NHMRC

Awarded by National Institute on Aging (NIA)

Funding Acknowledgements

We would like to thank the St Jude Children's Research Hospital Animal Resource Center's staff for their support and excellent animal care. We thank G. Lennon for the help with single-cell sorting. We thank the Hartwell Center at St Jude for sequencing support. We also thank M. Morris, L. McLaren, T. H. Oguin III, W. Awad, A. Zamora, D. Boyd, X. Guo, S. Valkenburg, E. Grant, N. Bird and N. Mifsud for their help in conducting experiments and preparation of the manuscript. The work was supported by NIH grant AI107625 and ALSAC (to P.G.T.), FHCRC internal development funding to P.B., and an NHMRC Program Grant (1071916) to K.K. and N. L. L. N. L. L. is the recipient of a Sylvia and Charles Viertel Senior Medical Research Fellowship. E.B.C. is an NHMRC Peter Doherty Fellow and K.K. is an NHMRC SRF Level B Fellow. G.C.W. was the recipient of National Institute on Aging (NIA) K23 AG033113, NIA P30 AG021334, John A. Hartford Foundation's Center of Excellence in Geriatric Medicine Scholars Award, and Johns Hopkins Biology of Healthy Aging Program.