Journal article
Transmission of influenza A(H1N1) 2009 pandemic viruses in Australian swine
YM Deng, P Iannello, I Smith, J Watson, IG Barr, P Daniels, N Komadina, B Harrower, FYK Wong
Influenza and Other Respiratory Viruses | WILEY-BLACKWELL | Published : 2012
Abstract
Background Swine have receptors for both human and avian influenza viruses and are a natural host for influenza A viruses. The 2009 influenza A(H1N1) pandemic (H1N1pdm) virus that was derived from avian, human and swine influenza viruses has infected pigs in various countries. Objectives To investigate the relationship between the H1N1pdm viruses isolated from piggery outbreaks in Australia and human samples associated with one of the outbreaks by phylogenetic analysis, and to determine whether there was any reassortment event occurring during the human-pig interspecies transmission. Methods Real-time RT-PCR and full genome sequencing were carried out on RNA isolated from nasal swabs and/or ..
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Funding Acknowledgements
We thank Prof. Anne Kelso for helpful discussion and critical reading of the manuscript. We also thank the state animal health divisions of the New South Wales, Queensland and Victoria Departments of Primary Industries for submissions of diagnostic pig samples; staff of the Darling Downs Public Health Unit for forwarding human clinical samples from the outbreak. The Melbourne WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health and Ageing.