Journal article

Incidence of pandemic (H1N1) 2009 influenza infection in children and pregnant women during the 2009 influenza season in Western Australia - a seroprevalence study

Gary K Dowse, David W Smith, Heath Kelly, Ian Barr, Karen L Laurie, Anthony R Jones, Anthony D Keil, Paul Effler



OBJECTIVE: To determine antibody levels and estimate incidence of infection with pandemic (H1N1) 2009 influenza in children and pregnant women during the 2009 winter in Western Australia. DESIGN, SETTING AND PARTICIPANTS: Two cross-sectional serosurveys using stored specimens collected for unrelated pathology testing, from before and after (3 August to 30 November 2009) circulation of the pandemic virus, and before commencement of the pandemic vaccination program. Specimens were from three groups: children aged 1-4 years, older children and teenagers aged 5-19 years, and pregnant women aged 21-45 years. The groups were geographically representative of the WA population. MAIN OUTCOME MEASURES..

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Funding Acknowledgements

We thank Charmaine Sutton, Louise Norbury and Deborah Noddy for assistance with selection and preparation of specimens. We also thank Louise Carolan for performing laboratory assays, Dr Lyn Waring for stewarding ethics applications, and Paul Saunders for helping with data analysis. The WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, is supported by the Australian Government Department of Health and Ageing.