Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing
Ian Barr, Aaron T Smith, Yanqiu Chen, Rachel Senturia, Judith N Burstyn, Feng Guo
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2012
Awarded by National Institutes of Health
We thank J. Valentine and K. Barnese for use of the anaerobic chamber, J. Feigon and T.C. Brunold for use of spectrophotometers, S. Weitz for sharing reagents, and M. Phillips in the University of California, Los Angeles-Department of Energy Biochemistry Instrumentation Facility for technical support. This project is supported by National Institutes of Health Grants GM080563 (to F.G.) and HL065217 (to J.N.B.).