Journal article

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

Ian Barr, Aaron T Smith, Yanqiu Chen, Rachel Senturia, Judith N Burstyn, Feng Guo

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2012

University of Melbourne Researchers


Awarded by National Institutes of Health

Funding Acknowledgements

We thank J. Valentine and K. Barnese for use of the anaerobic chamber, J. Feigon and T.C. Brunold for use of spectrophotometers, S. Weitz for sharing reagents, and M. Phillips in the University of California, Los Angeles-Department of Energy Biochemistry Instrumentation Facility for technical support. This project is supported by National Institutes of Health Grants GM080563 (to F.G.) and HL065217 (to J.N.B.).