Journal article

A chest radiograph scoring system in patients with severe acute respiratory infection: a validation study

Emma Taylor, Kathryn Haven, Peter Reed, Ange Bissielo, Dave Harvey, Colin McArthur, Cameron Bringans, Simone Freundlich, R Joan H Ingram, David Perry, Francessa Wilson, David Milne, Lucy Modahl, Q Sue Huang, Diane Gross, Marc-Alain Widdowson, Cameron C Grant

BMC MEDICAL IMAGING | BMC | Published : 2015

Abstract

BACKGROUND: The term severe acute respiratory infection (SARI) encompasses a heterogeneous group of respiratory illnesses. Grading the severity of SARI is currently reliant on indirect disease severity measures such as respiratory and heart rate, and the need for oxygen or intensive care. With the lungs being the primary organ system involved in SARI, chest radiographs (CXRs) are potentially useful for describing disease severity. Our objective was to develop and validate a SARI CXR severity scoring system. METHODS: We completed validation within an active SARI surveillance project, with SARI defined using the World Health Organization case definition of an acute respiratory infection with a..

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Grants

Awarded by US CDC


Awarded by National Center for Immunization and Respiratory Diseases (NCIRD)


Funding Acknowledgements

The SHIVERS project is a multicenter and multidisciplinary collaboration. Special thanks to these collaborating organizations for their commitment and support: Institute of Environmental Science and Research, Auckland District Health Board, Counties-Manukau District Health Board, University of Otago, University of Auckland, United States Centers for Disease Control and Prevention, and World Health Organization Collaborating Centre at St Jude Children's Research Hospital in Memphis, USA. Special thanks to: the research nurses at Auckland District Health Board; the research nurses at Counties-Manukau District Health Board; staff of the World Health Organization National Influenza Centre and Institute of Environmental Science and Research; the Health Intelligence Team, Institute of Environmental Science and Research; staff of the Auckland District Health Board laboratory and Counties-Manukau District Health Board laboratory; information technology staff; and SARI surveillance participants. In addition, special thanks to Dr. Dean Erdman from Gastroenteritis and Respiratory Viruses Laboratory Branch, US CDC, who provided the real-time PCR assay for non-influenza respiratory viruses. We also acknowledge the contribution of Dr. Catherine Gilchrist (PhD), medical writer, who edited the manuscript and assisted with the creation of tables and figures. The New Zealand Ministry of Health provided support in kind.The SHIVERS project is funded by US CDC (1U01IP000480-01). The involvement of Cameron Bringans and Simone Freundlich in this project was funding by a University of Auckland summer research studentship. The hospital-based surveillance is a key component of the SHIVERS project. The SHIVERS project is a five-year research cooperative agreement between ESR and US CDC's National Center for Immunization and Respiratory Diseases Influenza Division.