Journal article
Molecular epidemiology of group a streptococcus from pharyngeal isolates in Auckland, New Zealand, 2013
DA Williamson, NJ Moreland, P Carter, A Upton, J Morgan, T Proft, D Lennon, MG Baker, R Dunbar, JD Fraser
New Zealand Medical Journal | NEW ZEALAND MEDICAL ASSOC | Published : 2014
Abstract
Aims To describe the molecular epidemiology of emm types associated with circulating pharyngeal group A streptococcus (GAS) isolates in Auckland, New Zealand. Methods GAS isolates were collected over a 10-day period from a community pathology provider in Auckland. PCR analysis and sequencing of the emm gene was performed at the Institute of Environmental Science and Research. Results A total of 52 emm types were identified from 278 GAS isolates. The three most common emm types were emm1, emm89 and emm12. Overall, the experimental 30-valent GAS M protein vaccine covered 19 / 52 (37%) of emm types in our study. Discussion Our study provides baseline data on the circulating pharyngeal GAS emm t..
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Funding Acknowledgements
We thank the laboratory staff at LabTests Auckland for help with collecting isolates. This work was funded by a grant from the Maurice Wilkins Centre for Biodiscovery, University of Auckland. DAW is a Clinical Research Training Fellow of the Health Research Council of New Zealand.