Journal article

Central Line-Associated Bloodstream Infections in Adult Hematology Patients with Febrile Neutropenia: An Evaluation of Surveillance Definitions Using Differential Time to Blood Culture Positivity

Joshua T Freeman, Anna Elinder-Camburn, Catherine McClymont, Deverick J Anderson, Mary Bilkey, Deborah A Williamson, Leanne Berkahn, Sally A Roberts

Infection Control & Hospital Epidemiology | UNIV CHICAGO PRESS | Published : 2013

Abstract

We used differential time to positivity between central and peripheral blood cultures to evaluate the positive predictive value (PPV) of the National Healthcare Safety Network central line-associated bloodstream infection (CLABSI) surveillance definition among hematology patients with febrile neutropenia. The PPV was 27.7%, which suggests that, when the definition is applied to this population, CLABSI rates will be substantially overestimated.