Journal article

Escherichia coli Bloodstream Infection After Transrectal Ultrasound-Guided Prostate Biopsy: Implications of Fluoroquinolone-Resistant Sequence Type 131 as a Major Causative Pathogen

Deborah A Williamson, Sally A Roberts, David L Paterson, Hanna Sidjabat, Anna Silvey, Jonathan Masters, Michael Rice, Joshua T Freeman

CLINICAL INFECTIOUS DISEASES | OXFORD UNIV PRESS INC | Published : 2012

Abstract

BACKGROUND: Transrectal ultrasound-guided (TRUS) prostate biopsy is a commonly performed procedure, and fluoroquinolones are the most frequently given prophylactic antimicrobials. In the context of increasing fluoroquinolone resistance, and the international emergence of fluoroquinolone-resistant sequence type 131 (ST131) Escherichia coli, we describe a large series of E. coli bacteremia after TRUS biopsy. METHODS: All male patients admitted with community-onset (CO) E. coli bacteremia from January 2006 through December 2010 were included. Patient characteristics, treatment outcomes, and rates of antimicrobial resistance were compared between patients with TRUS biopsy-related bacteremia and ..

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