MORC1 represses transposable elements in the mouse male germline
William A Pastor, Hume Stroud, Kevin Nee, Wanlu Liu, Dubravka Pezic, Sergei Manakov, Serena A Lee, Guillaume Moissiard, Natasha Zamudio, Deborah Bourc'his, Alexei A Aravin, Amander T Clark, Steven E Jacobsen
Nature Communications | NATURE PUBLISHING GROUP | Published : 2014
Awarded by NIH
We acknowledge the UCLA BSCRC Flow Cytometry core for flow and FACS assistance, and the UCLA BSCRC High Throughput Sequencing Core. Bryan Cullen provided anti-IAP Gag antibody and Alexander Bortvin provided anti-LINE ORF1p antibody. Jiamu Du and Dinshaw Patel provided recombinant MORC1 coiled-coil domain to raise antibody. W.A.P. is supported by the Jane Coffin Childs Memorial Fund for Medical Research. H.S. is an HHMI Fellow of the Damon Runyon Cancer Research Foundation (DRG-2194-14). W.L. is supported by a grant from the Chinese Scholar Council. This work was supported by grants from the NIH (R01 HD058047 and DP2 OD007371A), a Research Award from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Nogradi Fund, the Searle Scholar and the Packard Fellowship Awards, and an ANR grant ("TranspoFertil"). S.E.J. is an investigator of the Howard Hughes Medical Institute.