Bacteraemia in Malawian neonates and young infants 2002-2007: a retrospective audit.
Amanda Gwee, Benjamin Coghlan, Dean Everett, Newton Chagoma, Amos Phiri, Lorna Wilson, Elizabeth Molyneux
BMJ Open | Published : 2012
OBJECTIVES: To assess the causes of bacteraemia in young infants and susceptibility to first-line antibiotics (benzylpenicillin plus gentamicin) at the Queen Elizabeth Central Hospital (QECH), Malawi during 2002-2007. DESIGN: Retrospective analysis of demographic and microbiological data using laboratory records. SETTING: QECH is Malawi's largest hospital with 7000 neonates admitted annually, 9% for septicaemia. PATIENTS: All infants aged 60 days or less admitted to QECH that had a blood culture taken over the 6-year period. MAIN OUTCOME MEASURES: 6754 blood cultures were taken. 3323 organisms were isolated: one-third were pathogens, two-thirds contaminants. Gram-positive organisms (53%) wer..View full abstract