From bench to bedside: Can the improvements in left ventricular assist device design mitigate adverse events and increase survival?
Vincenzo Tarzia, Gabriele Di Giammarco, Michele Di Mauro, Giacomo Bortolussi, Massimo Maccherini, Vincenzo Tursi, Massimo Maiani, Sonia Bernazzali, Daniele Marinelli, Massimiliano Foschi, Edward Buratto, Jonida Bejko, Dario Gregori, Silvia Scuri, Ugolino Livi, Guido Sani, Tomaso Bottio, Gino Gerosa
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY | MOSBY-ELSEVIER | Published : 2016
OBJECTIVE: In vitro tests demonstrated that the new cone-bearing configuration of the Jarvik 2000 (Jarvik Heart Inc, New York, NY) left ventricular assist device exhibits better hydraulic efficiency than the previous pin-bearing design. We investigated the long-term outcomes of patients who received the Jarvik 2000 left ventricular assist device, depending on bearing design. METHODS: A retrospective review of prospectively collected data from 18 centers included in the Italian Registry was performed. From May 2008 to September 2013, 99 patients with end-stage heart failure were enrolled. Patients were divided into 2 groups according to their Jarvik 2000 suspending mechanism: Group pin includ..View full abstract