AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Mengxia Gao; Yuning Hong; Bin Chen; Yinan Wang; Wenjun Zhou; Wallace WH Wong; Jian Zhou; Trevor A Smith; Zujin Zhao

Journal article

AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Mengxia Gao, Yuning Hong, Bin Chen, Yinan Wang, Wenjun Zhou, Wallace WH Wong, Jian Zhou, Trevor A Smith, Zujin Zhao

POLYMER CHEMISTRY | ROYAL SOC CHEMISTRY | Published : 2017

DOI: 10.1039/c7py00564d

Abstract

A series of new conjugated polyelectrolytes (CPEs) containing tetraphenylethene units are synthesized and characterized. They show apparent aggregation-induced emission (AIE) characteristics and give fluorescence covering from cyan to red with high emission efficiencies in aggregates. These AIE CPEs can directly enter and stain living cells for fluorescence imaging with low cytotoxicity, and can provide information on cellular viscosity at different locations based on fluorescence lifetime imaging.

University of Melbourne Researchers

Wallace Wong Author Chemistry

Trevor Smith Author Chemistry

Related Projects (9)

SELF-ORGANISED MATERIALS FOR FLEXIBLE ELECTRONICS

The emergence of organic electronics is transforming current electronic technologies that will lead to light-weight flexible devices such as..

Determining charge lifetime and mobility dynamics in organic semiconductors for photovoltaic applications

ARC CENTRE OF EXCELLENCE IN EXCITON SCIENCE (ARC CASH)

SELF-ORGANISED MATERIALS FOR FLEXIBLE ELECTRONICS

The emergence of organic electronics is transforming current electronic technologies that will lead to light-weight flexible devices such as..

ARC CENTRE OF EXCELLENCE IN EXCITON SCIENCE (ARC CASH- MATHS)

ARC CENTRE OF EXCELLENCE IN EXCITON SCIENCE (UOM CONTRIBUTION)

This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research p..

SPECTROSCOPY AND IMAGING PLATFORM FOR PHOTOACTIVE MATERIALS

This project aims to establish a comprehensive analytic tool-box to characterise solution-processable materials for thin-film solar cells ba..

Asian Research Network for Characterising Semi-Conducting Materials at High Spatial and Temporal Resolution

SPECTROSCOPY AND IMAGING PLATFORM FOR PHOTOACTIVE MATERIALS

This project aims to establish a comprehensive analytic tool-box to characterise solution-processable materials for thin-film solar cells ba..

Grants

Awarded by National Natural Science Foundation of China

Awarded by China Scholarship Council

Awarded by Guangdong Natural Science Funds for Distinguished Young Scholars

Awarded by Scientific Research Fund of Zhejiang Provincial Education Department

Awarded by Zhejiang Provincial Natural Science Foundation of China

Awarded by Fundamental Research Funds for the Central Universities

Funding Acknowledgements

We acknowledge the financial support from the National Natural Science Foundation of China (21404029, 21344007 and 21673082), the China Scholarship Council (201409645002), the Guangdong Natural Science Funds for Distinguished Young Scholars (2014A030306035), the Scientific Research Fund of Zhejiang Provincial Education Department (Y201121319), the Zhejiang Provincial Natural Science Foundation of China (LY14E30009) and the Fundamental Research Funds for the Central Universities (2017ZD001).