Journal article
Functional deficits of the attentional networks in autism
J Fan, S Bernardi, NT Van Dam, E Anagnostou, X Gu, L Martin, Y Park, X Liu, A Kolevzon, L Soorya, D Grodberg, E Hollander, PR Hof
Brain and Behavior | JOHN WILEY & SONS INC | Published : 2012
DOI: 10.1002/brb3.90
Abstract
Attentional dysfunction is among the most consistent observations of autism spectrum disorders (ASD). However, the neural nature of this deficit in ASD is still unclear. In this study, we aimed to identify the neurobehavioral correlates of attentional dysfunction in ASD. We used the Attention Network Test-Revised and functional magnetic resonance imaging to examine alerting, orienting, and executive control functions, as well as the neural substrates underlying these attentional functions in unmedicated, high-functioning adults with ASD (n = 12) and matched healthy controls (HC, n = 12). Compared with HC, individuals with ASD showed increased error rates in alerting and executive control, ac..
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Awarded by National Center for Research Resources (NCRR)
Awarded by National Institutes of Health (NIH)
Funding Acknowledgements
This work was supported by National Center for Research Resources (NCRR) Grant M01 RR000071. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of NCRR or National Institute of Mental Health (NIMH). This work was also supported in, part by, Seaver Autism Center for Research and Treatment at Mount Sinai School of Medicine, by National Institutes of Health (NIH) grant R21 MH083164 (to J. F.), and by the James S. McDonnell Foundation (to P. R. H.).