Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
Suneng Fu, Ling Yang, Ping Li, Oliver Hofmann, Lee Dicker, Winston Hide, Xihong Lin, Steven M Watkins, Alexander R Ivanov, Goekhan S Hotamisligil
Nature | NATURE PUBLISHING GROUP | Published : 2011
Awarded by National Institutes of Health
Awarded by NIH/NIEHS
Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
We thank A. Porter, E. Freeman and R. Davis for technical assistance. The anti-HERP antibody is a gift of Y. Hirabayashi. We thank the members of the G.S.H. laboratory for scientific discussions and critical reading of the manuscript. This work was supported in part by the National Institutes of Health (DK52539 and 1RC4-DK090942) and a research grant from Syndexa Pharmaceuticals to G.S.H. S.F. was supported in part by the NIH/NIEHS postdoctoral training grant (T32ES007155).