Conference Proceedings

A prospective randomized study to evaluate the renoprotective action of beating heart coronary surgery in low risk patients.

ATM Tang, J Knott, J Nanson, J Hsu, MP Haw, SK Ohri

Eur J Cardiothorac Surg | Published : 2002

Abstract

OBJECTIVES: Cardiopulmonary bypass (CPB) is widely regarded as an important contributor to renal failure, a well recognized complication following coronary artery surgery (coronary artery bypass grafting (CABG)). Anecdotally off-pump coronary surgery (OPCAB) is considered renoprotective. We examine the extent of renal glomerular and tubular injury in low-risk patients undergoing either OPCAB or on-pump coronary artery bypass (ONCAB). METHODS: Forty low-risk patients with normal preoperative cardiac and renal functions awaiting elective CABG were prospectively randomized into those undergoing OPCAB (n=20) and ONCAB (n=20). Glomerular and tubular injury were measured respectively by urinary ex..

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University of Melbourne Researchers