The application of decellularized human term fetal membranes in tissue engineering and regenerative medicine (TERM)

Abstract

Tissue engineering and regenerative medicine (TERM) is a field that applies biology and engineering principles to “restore, maintain or repair a tissue after injury”. Besides the potential to treat various diseases, these endeavours increase our understanding of fundamental cell biology. Although TERM has progressed rapidly, engineering a whole organ is still beyond our skills, primarily due to the complexity of tissues. Material science and current manufacturing methods are not capable of mimicking this complexity. Therefore, many researchers explore the use of naturally derived materials that maintain important biochemical, structural and mechanical properties of tissues. Consequently, emp..