Examining distinct working memory processes in children and adolescents using fMRI: Results and validation of a modified Brown-Peterson paradigm
Vanessa Siffredi, Pierre Barrouillet, Megan Spencer-Smith, Maarten Vaessen, Vicki Anderson, Patrik Vuilleumier
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2017
Verbal working memory (WM) comprises different processes (encoding, maintenance, retrieval) that are often compromised in brain diseases, but their neural correlates have not yet been examined in childhood and adolescence. To probe WM processes and associated neural correlates in developmental samples, and obtain comparable effects across different ages and populations, we designed an adapted Brown-Peterson task (verbal encoding and retrieval combined with verbal and visual concurrent tasks during maintenance) to implement during functional magnetic resonance imaging (fMRI). In a sample of typically developing children and adolescents (n = 16), aged 8 to 16 years, our paradigm successfully i..View full abstract
This study was supported by Victorian Governments Operational Infrastructure Support Program, the Murdoch Childrens Research Institute. VS was supported by the Swiss National Science Foundation Doc.CH scholarship. VA was supported by Australian National Health and Medical Research Council Senior Practitioner Fellowship.